Breast Surgery

Dr. David Mangiameli is a respected board-certified surgical oncologist. His dedicated expertise focuses on enhanced screening for high-risk patients, minimally invasive breast surgery, oncoplastic surgery, and customization of surgery for cancer in women who are universally and intrinsically unique. Dr. Mangiameli feels that there is a wide spectrum of options that lie between lumpectomy and mastectomy. Cancer removal is first and foremost; however, there are commonly more than just two surgical options.

Dr. Mangiameli is adamantly patient-centric. Subsequently, he practices evidence- based medicine with a comprehensive team that includes: medical oncologists, radiation oncologists, plastic surgeons, pathologists, and fellowship-trained women’s imagers (radiologists). All cancer patients are discussed at conferences attended by these cancer specialists. There are multiple cancer specialists involved simultaneously and from the beginning. This is why cancer center accreditation is so critical. This level of team involvement is what is required. Dr. Mangiameli’s program is the only accredited cancer center from Patchogue to Montauk and Orient. He has offices in Patchogue, Southampton, and Riverhead. Every site visit of Dr. Mangiameli’s team since 2014 by the American College of Surgeons has resulted in a perfect full accreditation.

Dr. Mangiameli performs all forms of breast and chest wall surgery. This includes minimally invasive breast surgery, complex oncoplastic surgery, chest wall resections and reconstruction, nipple-sparing and traditional mastectomies, sentinel lymph node mapping and biopsy, and full lymph node dissections. Additionally, he collaborates with his plastic surgery colleagues to achieve immediate reconstruction using implants and all forms of autologous flap reconstruction. In addition, he has extensive training and experience in screening and managing women who have high breast cancer risk from genetic mutations and other cumulative risk factors.

He has been a founding program director of a breast cancer center here in Suffolk County since 2014. Dr. Mangiameli has continuously provided the energy and leadership to compel and coordinate these clinical teams. Together they have treated thousands of women according to national guidelines. Additionally, he has been involved in many community outreach programs, including the NYS Cancer Screening Program. He also serves as a Police Surgeon for The New York State Troopers and the Police Surgeons Benevolent Association.

Dr. Mangiameli completed general surgery/trauma residency at The Brooklyn Hospital Center. He additionally completed a fellowship in Surgical Oncology at the National Institutes of Health, National Cancer Institute; a fellowship in Immunotherapy for Cancer also at the National Cancer Institute; and served as the SSO Fellow in Oncoplastic and Oncologic Breast Surgery at Columbia Presbyterian, College of Physicians and Surgeons, in NY.

Dr. Mangiameli has authored clinical and scientific textbook chapters, as well as peer-reviewed journal articles for his original work in genomics and small molecule drug analysis. Additionally, he administered clinical trials at the NIH and is a patent holder.

Dr. Mangiameli is foremost a father of two and also a musician and outdoors sportsman.

Dr Mangiameli has recently fostered a Surgical Mission in Ghana, a significant endeavor that underscores his commitment to global healthcare, which you can read more about in our Newsletter here

Credentials:  DO
Education & Training
   Residency:    The Brooklyn Hospital Center
   Fellowships:    National Institutes of Health, National Cancer Institute, Columbia Presbyterian, College of Physicians and Surgeons


Patient Reviews

  • "Dr. Mangamelli is so nice, thorough and you can tell he really cares. You’re not just a number.., He took care of my mom during her 2 times of breast cancer . He insisted he take care of me. He actually knows what tests work and what test are unnecessary I’ve never had a doctor so knowledgeable in that area. A+ doctor!"
      from Maria 5.0 Stars - (2025-07-11)
  • "The PA was wonderful! She made me feel at ease and that I was special to the practice. People outside were also very welcoming."
      from Kathy 5.0 Stars - (2025-07-10)
  • "As always, excellent care, very professional, and caring staff"
      from Mary 5.0 Stars - (2025-07-09)
  • "Words can't describe how amazing he is .I am very lucky my doctor referred me to him.thank you doctor for everything.very professional and friendly staff."
      from Maia 5.0 Stars - (2025-07-07)
  • "This practice is wonderful! Very caring staff!"
      from Susan 5.0 Stars - (2025-07-02)
  • "I wouldn’t trust anyone with my life other than Dr. Mangiameli. He and his staff are kind, warm, and caring. They are straight with the facts, but make sure you know that you are not alone, they are going to fight for and with you, and are comforting in some of the scariest moments you could experience. They are professional and personable. I’m so grateful and blessed to be in their care."
      from Meaghan 5.0 Stars - (2025-06-27)
  • "The staff is very kind and personable. The nurse I had was awesome also very sweet. Dr Mangiamelli is the best and his colleague..He is so friendly and makes you feel comfortable. Everything was nice great visit.😊"
      from Linda 5.0 Stars - (2025-06-25)
  • "Excellent staff. No wait time. Very personable PA."
      from Marcia 5.0 Stars - (2025-06-19)
  • "Great staff!"
      from Kristina 5.0 Stars - (2025-06-14)
  • "Dr.Mangiameli and his whole staff are awesome!!"
      from Justine 5.0 Stars - (2025-06-11)