Breast Surgery

Dr. David Mangiameli is a respected board-certified surgical oncologist. His dedicated expertise focuses on enhanced screening for high-risk patients, minimally invasive breast surgery, oncoplastic surgery, and customization of surgery for cancer in women who are universally and intrinsically unique. Dr. Mangiameli feels that there is a wide spectrum of options that lie between lumpectomy and mastectomy. Cancer removal is first and foremost; however, there are commonly more than just two surgical options.

Dr. Mangiameli is adamantly patient-centric. Subsequently, he practices evidence- based medicine with a comprehensive team that includes: medical oncologists, radiation oncologists, plastic surgeons, pathologists, and fellowship-trained women’s imagers (radiologists). All cancer patients are discussed at conferences attended by these cancer specialists. There are multiple cancer specialists involved simultaneously and from the beginning. This is why cancer center accreditation is so critical. This level of team involvement is what is required. Dr. Mangiameli’s program is the only accredited cancer center from Patchogue to Montauk and Orient. He has offices in Patchogue, Southampton, and Riverhead. Every site visit of Dr. Mangiameli’s team since 2014 by the American College of Surgeons has resulted in a perfect full accreditation.

Dr. Mangiameli performs all forms of breast and chest wall surgery. This includes minimally invasive breast surgery, complex oncoplastic surgery, chest wall resections and reconstruction, nipple-sparing and traditional mastectomies, sentinel lymph node mapping and biopsy, and full lymph node dissections. Additionally, he collaborates with his plastic surgery colleagues to achieve immediate reconstruction using implants and all forms of autologous flap reconstruction. In addition, he has extensive training and experience in screening and managing women who have high breast cancer risk from genetic mutations and other cumulative risk factors.

He has been a founding program director of a breast cancer center here in Suffolk County since 2014. Dr. Mangiameli has continuously provided the energy and leadership to compel and coordinate these clinical teams. Together they have treated thousands of women according to national guidelines. Additionally, he has been involved in many community outreach programs, including the NYS Cancer Screening Program. He also serves as a Police Surgeon for The New York State Troopers and the Police Surgeons Benevolent Association.

Dr. Mangiameli completed general surgery/trauma residency at The Brooklyn Hospital Center. He additionally completed a fellowship in Surgical Oncology at the National Institutes of Health, National Cancer Institute; a fellowship in Immunotherapy for Cancer also at the National Cancer Institute; and served as the SSO Fellow in Oncoplastic and Oncologic Breast Surgery at Columbia Presbyterian, College of Physicians and Surgeons, in NY.

Dr. Mangiameli has authored clinical and scientific textbook chapters, as well as peer-reviewed journal articles for his original work in genomics and small molecule drug analysis. Additionally, he administered clinical trials at the NIH and is a patent holder.

Dr. Mangiameli is foremost a father of two and also a musician and outdoors sportsman.

Dr Mangiameli has recently fostered a Surgical Mission in Ghana, a significant endeavor that underscores his commitment to global healthcare, which you can read more about in our Newsletter here

Credentials:  DO
Education & Training
   Residency:    The Brooklyn Hospital Center
   Fellowships:    National Institutes of Health, National Cancer Institute, Columbia Presbyterian, College of Physicians and Surgeons


Patient Reviews

  • "Once I signed in, I waited 5 - 10 minutes and was called into office. The staff are very courteous and professional. I feel at ease when I come to this office."
      from Claudette 5.0 Stars - (2025-03-22)
  • "Knowledgeable and caring staff."
      from F. 5.0 Stars - (2025-03-15)
  • "I wish I could click 20 stars ! Wonderful people, that always make me feel safe. Dr Mangiameli is the very bestđź’—"
      from Barbara 5.0 Stars - (2025-03-14)
  • "I can’t tell you how at ease I felt at my visit. The woman checking me me in was so warm and kind immediately calming. This is such a rarity today. The assistant who took my vitals and information was so sweet and professional. Dr Mangiameli was also so professional and informative and nice. I have to say from beginning to end of visit I was so pleasantly impressed."
      from Luisa 5.0 Stars - (2025-03-07)
  • "There are no words to express my extreme gratitude to NY Breast Health. Dr. Mangiameli and his total team of health professionals in the office and at the hospital eased my fears, held my hand and gave me love and support from beginning to end throughout my medical journey. I was blessed to have a great group of caring professionals by my side! Thank you ❤️ R. Christopher"
      from Robin 5.0 Stars - (2025-03-06)
  • "I had questions regarding my upcoming surgery. Dr Mangiameli took time from his busy day to answer all my questions. He is a very caring Doctor."
      from Deb 5.0 Stars - (2025-03-06)
  • "The staff is always very friendly! Any questions or concerns that come up they answer with detail and a full understanding of my history. Great staff and very clean as well!"
      from Corrine 5.0 Stars - (2025-03-05)
  • "(Translated by Google) Very professional. Excellent. Attention, there is a lot of human heat. (Original) Muy profecional Exelente. AtenciĂłn hay mucho Calor humano."
      from Juana 5.0 Stars - (2025-03-01)
  • "When a person has an appointment concerning breast cancer you can imagine the fear and worry it engenders. Knowing that It is Dr. Mangiameli’s office I am going to, a light shines for me in a dark time. Everyone there shows you the utmost concern for your situation. They understand where you are coming from. You feel confident though their treatment of you , and of course having Dr. Mangiameli for you doctor, that you are in the best place possible at this time in your life. I am lucky. I am cancer free❣️ Initially it was thought that I did have cancer as associated with having the BRCA gene. My Mother and, recently, my sister had breast cancer. An MRI diagnosed me with cancer in my left breast. A follow-up MRI to localize the cancer showed I had no cancer ! So I know both sides of being diagnosed with cancer and being cancer-free (and hoping to stay that way) My Mamogram and MRI this week still shows me cancer-free. This visit to the office was to affirm that finding. I arrived at the office en-veloped in that same caring, really loving atmosphere I associate with Dr.Mangiameli and all his staff. I am lucky to not have cancer, and luckier that I found a light in a dark time. Sincerely, Maureen See you next year🙋‍♀️"
      from maureen 5.0 Stars - (2025-02-27)
  • "Very friendly staff, easy to get an appointment and never a long wait! Dr. Mangiameli, Niger and Alissa are all caring, knowledgeable and professional providers."
      from Kim 5.0 Stars - (2025-02-23)