Breast Surgery

Dr. David Mangiameli is a respected board-certified surgical oncologist. His dedicated expertise focuses on enhanced screening for high-risk patients, minimally invasive breast surgery, oncoplastic surgery, and customization of surgery for cancer in women who are universally and intrinsically unique. Dr. Mangiameli feels that there is a wide spectrum of options that lie between lumpectomy and mastectomy. Cancer removal is first and foremost; however, there are commonly more than just two surgical options.

Dr. Mangiameli is adamantly patient-centric. Subsequently, he practices evidence- based medicine with a comprehensive team that includes: medical oncologists, radiation oncologists, plastic surgeons, pathologists, and fellowship-trained women’s imagers (radiologists). All cancer patients are discussed at conferences attended by these cancer specialists. There are multiple cancer specialists involved simultaneously and from the beginning. This is why cancer center accreditation is so critical. This level of team involvement is what is required. Dr. Mangiameli’s program is the only accredited cancer center from Patchogue to Montauk and Orient. He has offices in Patchogue, Southampton, and Riverhead. Every site visit of Dr. Mangiameli’s team since 2014 by the American College of Surgeons has resulted in a perfect full accreditation.

Dr. Mangiameli performs all forms of breast and chest wall surgery. This includes minimally invasive breast surgery, complex oncoplastic surgery, chest wall resections and reconstruction, nipple-sparing and traditional mastectomies, sentinel lymph node mapping and biopsy, and full lymph node dissections. Additionally, he collaborates with his plastic surgery colleagues to achieve immediate reconstruction using implants and all forms of autologous flap reconstruction. In addition, he has extensive training and experience in screening and managing women who have high breast cancer risk from genetic mutations and other cumulative risk factors.

He has been a founding program director of a breast cancer center here in Suffolk County since 2014. Dr. Mangiameli has continuously provided the energy and leadership to compel and coordinate these clinical teams. Together they have treated thousands of women according to national guidelines. Additionally, he has been involved in many community outreach programs, including the NYS Cancer Screening Program. He also serves as a Police Surgeon for The New York State Troopers and the Police Surgeons Benevolent Association.

Dr. Mangiameli completed general surgery/trauma residency at The Brooklyn Hospital Center. He additionally completed a fellowship in Surgical Oncology at the National Institutes of Health, National Cancer Institute; a fellowship in Immunotherapy for Cancer also at the National Cancer Institute; and served as the SSO Fellow in Oncoplastic and Oncologic Breast Surgery at Columbia Presbyterian, College of Physicians and Surgeons, in NY.

Dr. Mangiameli has authored clinical and scientific textbook chapters, as well as peer-reviewed journal articles for his original work in genomics and small molecule drug analysis. Additionally, he administered clinical trials at the NIH and is a patent holder.

Dr. Mangiameli is foremost a father of two and also a musician and outdoors sportsman.

Dr Mangiameli has recently fostered a Surgical Mission in Ghana, a significant endeavor that underscores his commitment to global healthcare, which you can read more about in our Newsletter here

Credentials:  DO
Education & Training
   Residency:    The Brooklyn Hospital Center
   Fellowships:    National Institutes of Health, National Cancer Institute, Columbia Presbyterian, College of Physicians and Surgeons


Patient Reviews

  • "Dr. Mangiameli was so caring and kind. He made me feel at ease, and I know I came to the right place!"
      from Anastasia 5.0 Stars - (2025-08-20)
  • "Everyone i dealt with was patient, gentle and helpful."
      from annmarie 5.0 Stars - (2025-08-19)
  • "Arrived on time and was seen within 5 minutes. Thorough exam and answered question. Very good care."
      from Patricia 5.0 Stars - (2025-08-19)
  • "The office was spotless. The receptionist was kind and cheerful along with the young lady who took my vitals. Dr mangiameli was also professional. He listened and answered each question i had,while explaining, in detail, his findings."
      from Susan 5.0 Stars - (2025-08-15)
  • "Always a pleasant experience!"
      from Patricia 5.0 Stars - (2025-08-12)
  • "Family away from home. Im trily blessed with the staff. God bless them."
      from Daiana 5.0 Stars - (2025-08-11)
  • "Wonderful experience at this practice. Great communication with the practitioner who was very easy to speak with. She also gave a thorough physical exam."
      from Patricia 5.0 Stars - (2025-08-08)
  • "Dr. Mangiameli was very informative and put me at ease. He clearly explained all my health concerns . He and his staff are very compassionate professionals."
      from Angela 5.0 Stars - (2025-08-06)
  • "I had the most awesome experience.. From the front desk until I went in with Dr. Mangiameli.. Made the appointment very calming. Any fears were erased. He took the time to explain everything which put my mind at ease.. the entire staff was excellent."
      from Susan 5.0 Stars - (2025-08-06)
  • "My husband and I were met with professional, kind and compassionate staff during each visit. Dr.Mangiomelli is a fantastic doctor, who took the time to explain in detail every question, fear and concern we had. Our experience is a textbook example of patient centered care on every level. We have complete confidence in Dr. Mangiomelli and all of his staff. I would highly recommend him.."
      from Lisa 5.0 Stars - (2025-08-05)