Breast Surgery
Dr. David Mangiameli is a respected board-certified surgical oncologist. His dedicated expertise focuses on enhanced screening for high-risk patients, minimally invasive breast surgery, oncoplastic surgery, and customization of surgery for cancer in women who are universally and intrinsically unique. Dr. Mangiameli feels that there is a wide spectrum of options that lie between lumpectomy and mastectomy. Cancer removal is first and foremost; however, there are commonly more than just two surgical options.
Dr. Mangiameli is adamantly patient-centric. Subsequently, he practices evidence- based medicine with a comprehensive team that includes: medical oncologists, radiation oncologists, plastic surgeons, pathologists, and fellowship-trained women’s imagers (radiologists). All cancer patients are discussed at conferences attended by these cancer specialists. There are multiple cancer specialists involved simultaneously and from the beginning. This is why cancer center accreditation is so critical. This level of team involvement is what is required. Dr. Mangiameli’s program is the only accredited cancer center from Patchogue to Montauk and Orient. He has offices in Patchogue, Southampton, and Riverhead. Every site visit of Dr. Mangiameli’s team since 2014 by the American College of Surgeons has resulted in a perfect full accreditation.
Dr. Mangiameli performs all forms of breast and chest wall surgery. This includes minimally invasive breast surgery, complex oncoplastic surgery, chest wall resections and reconstruction, nipple-sparing and traditional mastectomies, sentinel lymph node mapping and biopsy, and full lymph node dissections. Additionally, he collaborates with his plastic surgery colleagues to achieve immediate reconstruction using implants and all forms of autologous flap reconstruction. In addition, he has extensive training and experience in screening and managing women who have high breast cancer risk from genetic mutations and other cumulative risk factors.
He has been a founding program director of a breast cancer center here in Suffolk County since 2014. Dr. Mangiameli has continuously provided the energy and leadership to compel and coordinate these clinical teams. Together they have treated thousands of women according to national guidelines. Additionally, he has been involved in many community outreach programs, including the NYS Cancer Screening Program. He also serves as a Police Surgeon for The New York State Troopers and the Police Surgeons Benevolent Association.
Dr. Mangiameli completed general surgery/trauma residency at The Brooklyn Hospital Center. He additionally completed a fellowship in Surgical Oncology at the National Institutes of Health, National Cancer Institute; a fellowship in Immunotherapy for Cancer also at the National Cancer Institute; and served as the SSO Fellow in Oncoplastic and Oncologic Breast Surgery at Columbia Presbyterian, College of Physicians and Surgeons, in NY.
Dr. Mangiameli has authored clinical and scientific textbook chapters, as well as peer-reviewed journal articles for his original work in genomics and small molecule drug analysis. Additionally, he administered clinical trials at the NIH and is a patent holder.
Dr. Mangiameli is foremost a father of two and also a musician and outdoors sportsman.
Dr Mangiameli has recently fostered a Surgical Mission in Ghana, a significant endeavor that underscores his commitment to global healthcare, which you can read more about in our Newsletter here
| John T Mather Memorial Hospital |
| Long Island Community Hospital |
| Peconic Bay Medical Center |
| St. Catherine Of Siena Medical Center |
Patient Reviews
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"ALL of the staff at this office is excellent and I’ve never had an appointment that wasn’t on time!"
from A 5.0 Stars - (2025-11-01) -
"Office staff was great. Would recommend Dr. Mangiameli to everyone! Every thing about my experience was great."
from Barbara 5.0 Stars - (2025-10-25) -
"Love this place, Dr is wonderful & caring and so is the PA."
from Joanne 5.0 Stars - (2025-10-23) -
"For most women, the thought of any type of breast surgery is stressful. However, the moment I opened the door to Dr. Mangiameli’s office.and met Lydia, the receptionist,, my anxiety vanished. There is a sense of calm and happiness in the office. Every one smiles and when I met Dr. M, he made me feel as if I was his only patient . He took the time to have a conversation with me. I felt he saw me as a person, not just a patient In a long queue of patients,
I highly recommend him."
from Athene 5.0 Stars - (2025-10-20) -
"Extremely helpful and kind office with caring and supportive employees. Highly recommend the office and team of Dr Mangiameli."
from Dawn 5.0 Stars - (2025-10-17) -
"I absolutely love Dr. Mangiameli & his staff ! They are so kind & helpful. I’m a few weeks post surgery & still call them with questions & they are always there to help. I would highly recommend them !"
from Lauren 5.0 Stars - (2025-10-17) -
"Very friendly staff. Excellent office👍🏼👍🏼"
from Louise 5.0 Stars - (2025-10-12) -
"The staff, PA’s, and doctors are amazing! Caring, understanding and helpful. They run on time and work with you on scheduling appointments."
from Lisa 5.0 Stars - (2025-10-11) -
"Office staff were very friendly and the Dr was so professional and personable"
from Jeanne 5.0 Stars - (2025-10-11) -
"I had a good first visit and meeting with
Dr. David Mangiameli. He listens to you and explains any questions you may have.
I’ve been a Memorial Sloan Kettering patient since 1905, and have switched do to long distance traveling.. very grateful to have found Dr. Mangiameli!"
from Dawn 5.0 Stars - (2025-10-10)