Breast Surgery

Dr. David Mangiameli is a respected board-certified surgical oncologist. His dedicated expertise focuses on enhanced screening for high-risk patients, minimally invasive breast surgery, oncoplastic surgery, and customization of surgery for cancer in women who are universally and intrinsically unique. Dr. Mangiameli feels that there is a wide spectrum of options that lie between lumpectomy and mastectomy. Cancer removal is first and foremost; however, there are commonly more than just two surgical options.

Dr. Mangiameli is adamantly patient-centric. Subsequently, he practices evidence- based medicine with a comprehensive team that includes: medical oncologists, radiation oncologists, plastic surgeons, pathologists, and fellowship-trained women’s imagers (radiologists). All cancer patients are discussed at conferences attended by these cancer specialists. There are multiple cancer specialists involved simultaneously and from the beginning. This is why cancer center accreditation is so critical. This level of team involvement is what is required. Dr. Mangiameli’s program is the only accredited cancer center from Patchogue to Montauk and Orient. He has offices in Patchogue, Southampton, and Riverhead. Every site visit of Dr. Mangiameli’s team since 2014 by the American College of Surgeons has resulted in a perfect full accreditation.

Dr. Mangiameli performs all forms of breast and chest wall surgery. This includes minimally invasive breast surgery, complex oncoplastic surgery, chest wall resections and reconstruction, nipple-sparing and traditional mastectomies, sentinel lymph node mapping and biopsy, and full lymph node dissections. Additionally, he collaborates with his plastic surgery colleagues to achieve immediate reconstruction using implants and all forms of autologous flap reconstruction. In addition, he has extensive training and experience in screening and managing women who have high breast cancer risk from genetic mutations and other cumulative risk factors.

He has been a founding program director of a breast cancer center here in Suffolk County since 2014. Dr. Mangiameli has continuously provided the energy and leadership to compel and coordinate these clinical teams. Together they have treated thousands of women according to national guidelines. Additionally, he has been involved in many community outreach programs, including the NYS Cancer Screening Program. He also serves as a Police Surgeon for The New York State Troopers and the Police Surgeons Benevolent Association.

Dr. Mangiameli completed general surgery/trauma residency at The Brooklyn Hospital Center. He additionally completed a fellowship in Surgical Oncology at the National Institutes of Health, National Cancer Institute; a fellowship in Immunotherapy for Cancer also at the National Cancer Institute; and served as the SSO Fellow in Oncoplastic and Oncologic Breast Surgery at Columbia Presbyterian, College of Physicians and Surgeons, in NY.

Dr. Mangiameli has authored clinical and scientific textbook chapters, as well as peer-reviewed journal articles for his original work in genomics and small molecule drug analysis. Additionally, he administered clinical trials at the NIH and is a patent holder.

Dr. Mangiameli is foremost a father of two and also a musician and outdoors sportsman.

Dr Mangiameli has recently fostered a Surgical Mission in Ghana, a significant endeavor that underscores his commitment to global healthcare, which you can read more about in our Newsletter here

Credentials:  DO
Education & Training
   Residency:    The Brooklyn Hospital Center
   Fellowships:    National Institutes of Health, National Cancer Institute, Columbia Presbyterian, College of Physicians and Surgeons


Patient Reviews

  • "Dr. Mangiameli, and his exemplary office and health-care staff, are consistently kind, smart, up-to-date, cordial and well prepared to assist their patients. Five stars isn't enough to describe the exceptional, caring and professional service this team always provides!"
      from Dorothy 5.0 Stars - (2025-05-28)
  • "Very knowledgeable, takes the time to listen to you. All the staff were very kind"
      from LauraJean 5.0 Stars - (2025-05-28)
  • "Wonderful atmosphere. Felt very comfortable there"
      from Ellen 5.0 Stars - (2025-05-27)
  • "Dr. Mangiameli explained his training and that of the other woman in the room. He was kind and caring. They were accommodating and made me feel more at ease."
      from Tricia 5.0 Stars - (2025-05-21)
  • "Very informative and comfortable visit. Perfect in every way."
      from Dolores 5.0 Stars - (2025-05-16)
  • "Dr Mangiamli is always respectful and concerned about your well being. I trust him completely Wonderful feeling to trust your doctor to such a degree"
      from Marianne 5.0 Stars - (2025-05-15)
  • "I can't say enough wonderful accolades about Dr. Mangiamelli. He is truly the best in his profession!!"
      from lorriane 5.0 Stars - (2025-05-11)
  • "Everyone was wonderful. It’s so convenient to have my mammogram and Dr. Mangiameli in the same building and the Westhampton Beach office is close by and easy to find."
      from Meredith 5.0 Stars - (2025-05-09)
  • "I can’t say enough about Dr. Mangiamelli, an oncological surgeon who’s truly one of a kind. He’s the most caring doctor I’ve ever met, with a warmth that puts you at ease from the moment you meet him. He takes the time to explain everything in a way that’s clear and reassuring, never rushing, always making sure you feel heard and understood. His skill is nothing short of remarkable—after my surgery, I was stunned to see he left no visible scar, a testament to his precision and care. He’s flexible, thoughtful, and goes above and beyond in ways that make you feel like you’re in the best possible hands. His staff? They’re just as wonderful. They’re kind, accommodating, and the sort of people who make you feel like family. Every visit to their clinic is a breath of fresh air—it’s modern, spotlessly clean, and has this bright, airy vibe that lifts your spirits. Honestly, it’s a pleasure to be there, which is saying something for a medical office. Dr. Mangiamelli and his team have created something special, and I’m so grateful for the care they provide."
      from Olivia 5.0 Stars - (2025-05-09)
  • "(Translated by Google) They have an excellent team of professionals and great attention. They are very professional in all their dealings. (Original) Tiene un excelente equipo de profesionales y una gran atencion.muy profesionales en todos sus tratos"
      from evelyn 5.0 Stars - (2025-05-09)