Breast Surgery
Dr. David Mangiameli is a respected board-certified surgical oncologist. His dedicated expertise focuses on enhanced screening for high-risk patients, minimally invasive breast surgery, oncoplastic surgery, and customization of surgery for cancer in women who are universally and intrinsically unique. Dr. Mangiameli feels that there is a wide spectrum of options that lie between lumpectomy and mastectomy. Cancer removal is first and foremost; however, there are commonly more than just two surgical options.
Dr. Mangiameli is adamantly patient-centric. Subsequently, he practices evidence- based medicine with a comprehensive team that includes: medical oncologists, radiation oncologists, plastic surgeons, pathologists, and fellowship-trained women’s imagers (radiologists). All cancer patients are discussed at conferences attended by these cancer specialists. There are multiple cancer specialists involved simultaneously and from the beginning. This is why cancer center accreditation is so critical. This level of team involvement is what is required. Dr. Mangiameli’s program is the only accredited cancer center from Patchogue to Montauk and Orient. He has offices in Patchogue, Southampton, and Riverhead. Every site visit of Dr. Mangiameli’s team since 2014 by the American College of Surgeons has resulted in a perfect full accreditation.
Dr. Mangiameli performs all forms of breast and chest wall surgery. This includes minimally invasive breast surgery, complex oncoplastic surgery, chest wall resections and reconstruction, nipple-sparing and traditional mastectomies, sentinel lymph node mapping and biopsy, and full lymph node dissections. Additionally, he collaborates with his plastic surgery colleagues to achieve immediate reconstruction using implants and all forms of autologous flap reconstruction. In addition, he has extensive training and experience in screening and managing women who have high breast cancer risk from genetic mutations and other cumulative risk factors.
He has been a founding program director of a breast cancer center here in Suffolk County since 2014. Dr. Mangiameli has continuously provided the energy and leadership to compel and coordinate these clinical teams. Together they have treated thousands of women according to national guidelines. Additionally, he has been involved in many community outreach programs, including the NYS Cancer Screening Program. He also serves as a Police Surgeon for The New York State Troopers and the Police Surgeons Benevolent Association.
Dr. Mangiameli completed general surgery/trauma residency at The Brooklyn Hospital Center. He additionally completed a fellowship in Surgical Oncology at the National Institutes of Health, National Cancer Institute; a fellowship in Immunotherapy for Cancer also at the National Cancer Institute; and served as the SSO Fellow in Oncoplastic and Oncologic Breast Surgery at Columbia Presbyterian, College of Physicians and Surgeons, in NY.
Dr. Mangiameli has authored clinical and scientific textbook chapters, as well as peer-reviewed journal articles for his original work in genomics and small molecule drug analysis. Additionally, he administered clinical trials at the NIH and is a patent holder.
Dr. Mangiameli is foremost a father of two and also a musician and outdoors sportsman.
Dr Mangiameli has recently fostered a Surgical Mission in Ghana, a significant endeavor that underscores his commitment to global healthcare, which you can read more about in our Newsletter here
| John T Mather Memorial Hospital |
| Long Island Community Hospital |
| Peconic Bay Medical Center |
| St. Catherine Of Siena Medical Center |
Patient Reviews
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"Professional and trustworthy."
from Margaret 5.0 Stars - (2025-07-30) -
"I went for an office visit, the nurse is very personable and answers any questions I may have."
from Debbie 5.0 Stars - (2025-07-30) -
"Best breast doctor around. Had breast cancer and Dr mangimelli was the best kind caring makes you feel so much better Dolores Schwarz"
from Dolores 5.0 Stars - (2025-07-27) -
"From the moment I walked into the office, I felt genuinely cared for. Dr. Mangiameli took the time to listen—truly listen—to all of my concerns, fears, and questions. This wasn't just a medical appointment; it was a compassionate, empowering experience during one of the most vulnerable times of my life.
Dr. Mangiameli explained everything clearly and patiently, ensuring I understood my diagnosis, surgical options, and next steps. He balanced medical expertise with empathy in a way that immediately built trust. I never felt rushed or like just another patient—every interaction was thoughtful and focused entirely on what was best for me, both physically and emotionally. Dr. Mangiameli is a doctor of course but a person who made me laugh and laughed with me. No superiority at this facility just warm, knowledgeable, friendly and professional.
The team was equally phenomenal—warm, organized, and supportive from start to finish. If you’re looking for a breast cancer surgeon who combines unmatched skill with sincere compassion, I cannot recommend Dr. Mangiameli highly enough. This consultation gave me not just clarity, but hope."
from Elizabeth 5.0 Stars - (2025-07-25) -
"The staff at Dr. Mangiameli’s practice are so warm & friendly.
Office is run so efficiently. I always feel so well taken care of.
Beyond excellent.. Highly recommend!"
from Eileen 5.0 Stars - (2025-07-19) -
"The doctor was very nice and he was extremely patient. He was thorough and kept my mind at ease."
from Kim 5.0 Stars - (2025-07-16) -
"The staff was amazing. The PA was very personable and also gave me the time and asked me if I had any questions. I give it a 10 out of 10."
from Lisa 5.0 Stars - (2025-07-12) -
"Dr. Mangamelli is so nice, thorough and you can tell he really cares. You’re not just a number.., He took care of my mom during her 2 times of breast cancer . He insisted he take care of me. He actually knows what tests work and what test are unnecessary I’ve never had a doctor so knowledgeable in that area. A+ doctor!"
from Maria 5.0 Stars - (2025-07-11) -
"The PA was wonderful! She made me feel at ease and that I was special to the practice. People outside were also very welcoming."
from Kathy 5.0 Stars - (2025-07-10) -
"As always, excellent care, very professional, and caring staff"
from Mary 5.0 Stars - (2025-07-09)